CV & Publications

Michael Daniels CV_Current


Moudio S, Willis A, Pytka K, Abulkassim R, Brett RR, Webster JF, Wozny C, Barbour M, Jiang H, Watson DG, van Kralingen JC, MacKenzie SM, Daniels MJD, McColl BW, Sossick S, Nuthall HN, Bushell TJ. Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines. Psychopharmacology. 2022

Rifai OM, Longden J , O’Shaughnessy J, Sewell MDE, McDade K, Daniels MJD, Abrahams S, Chandran S, McColl B , Sibley CR, Gregory JM. Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis. BioRXiv. 2021

McCulloch L, Harris AJ, Malbon A, Daniels MJD, Younas M, Grainger JR, Allan SM, Smith CJ, McColl BW. Treatment with IgM-enriched intravenous immunoglobulins (IgM-IVIg) enhances clearance of stroke-associated bacterial lung infection. BioRXiv. 2021 (accepted in Immunology)

Rivers-Auty J, Tapia VS, White CS, Daniels MJD, Drinkall S, Kennedy PT, Spence HG, Yu S, Green JP, Hoyle C, Cook J, Bradley A, Mather AE, Peters R, Tzeng T, Gordon MJ, Beattie JH, Brough D and Lawrence CB. Zinc Status Alters Alzheimer’s Disease Progression through NLRP3-Dependent Inflammation. Journal of Neuroscience. 2021

Tzioras M, Daniels MJD, King D, Popovic K, Holloway RK, Stevenson AJ, Tulloch J, Kandasamy J, Sokol D, Latta C, Rose J, Smith C,  Miron VE,  Henstridge C, McColl BW,  Spires-Jones TL. Altered synaptic ingestion by human microglia in Alzheimer’s disease. BioRXiv. 2019

Tapia VS, Daniels MJD, Palazón-Riquelme P, Dewhurst M, Luheshi NM, Rivers-Auty J, Green J, Redondo-Castro E, Kaldis P, Lopez-Castejon G, Brough D. The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes. J Biol Chem. 2019.

Rivers-Auty J, Daniels MJD, Colliver I, Robertson D, Brough D. Redefining the ancestral origins of the interleukin-1 superfamily. Nature Communications. 2018. 9:1156

Daniels MJD, Adamson AD, Humphreys N, Brough D. CRISPR/Cas9 mediated mutation of mouse IL-1α nuclear localisation sequence abolishes expression. Scientific Reports. 2017. 

Baldwin AG, Rivers-Auty J, Daniels MJD, White CS, Schwalbe CH, Schilling T, Hammadi H, Jaiyong P, Spencer N, England H, Luheshi N, Kadirvel M, Lawrence CB, Rothwell NJ, Harte MK, Bryce RA, Allan SM, Eder C, Freeman S, Brough D. New boron based inhibitors of the NLRP3 inflammasome. Cell Chemical Biology. 2017.

Daniels MJD, Brough D. Unconventional Pathways of Secretion Contribute to Inflammation. Int J Mol Sci. 2017. 5;18

Huang SW, Walker C, Pennock J, Else K, Muller W, Daniels MJD, Pellegrini C, Brough D, Lopez-Castejon G, Cruickshank SM. P2X7 receptor-dependent tuning of gut epithelial responses to infection. Immunol. Cell Biol. 2017. 95:178-88

Daniels MJD, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth S, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models. Nature Communications. 2016. 7:12504

Martín-Sánchez F, Diamond C, Zeitler M, Gomez-Sanchez A, Baroja-Mazo A, Bagnall J, Spiller D, White M, Mortellaro A, Peñalver M, Daniels MJD, Paszek P, Steringer JP, Nickel W, Brough D*, Pelegrín P*. Inflammasome-dependent IL-1β release depends upon membrane permeabilisation. Cell Death and Differentiation. 2016. 23:1219-31