CV & Publications

Michael Daniels CV


Tapia VS, Daniels MJD, Palazón-Riquelme P, Dewhurst M, Luheshi NM, Rivers-Auty J, Green J, Redondo-Castro E, Kaldis P, Lopez-Castejon G, Brough D. The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes. J Biol Chem. 2019.

Rivers-Auty J, Daniels MJD, Colliver I, Robertson D, Brough D. Redefining the ancestral origins of the interleukin-1 superfamily. Nature Communications. 2018. 9:1156

Daniels MJD, Adamson AD, Humphreys N, Brough D. CRISPR/Cas9 mediated mutation of mouse IL-1α nuclear localisation sequence abolishes expression. Scientific Reports. 2017. 

Baldwin AG, Rivers-Auty J, Daniels MJD, White CS, Schwalbe CH, Schilling T, Hammadi H, Jaiyong P, Spencer N, England H, Luheshi N, Kadirvel M, Lawrence CB, Rothwell NJ, Harte MK, Bryce RA, Allan SM, Eder C, Freeman S, Brough D. New boron based inhibitors of the NLRP3 inflammasome. Cell Chemical Biology. 2017.

Daniels MJD, Brough D. Unconventional Pathways of Secretion Contribute to Inflammation. Int J Mol Sci. 2017. 5;18

Huang SW, Walker C, Pennock J, Else K, Muller W, Daniels MJD, Pellegrini C, Brough D, Lopez-Castejon G, Cruickshank SM. P2X7 receptor-dependent tuning of gut epithelial responses to infection. Immunol. Cell Biol. 2017. 95:178-88

Daniels MJD, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth S, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models. Nature Communications. 2016. 7:12504

Martín-Sánchez F, Diamond C, Zeitler M, Gomez-Sanchez A, Baroja-Mazo A, Bagnall J, Spiller D, White M, Mortellaro A, Peñalver M, Daniels MJD, Paszek P, Steringer JP, Nickel W, Brough D*, Pelegrín P*. Inflammasome-dependent IL-1β release depends upon membrane permeabilisation. Cell Death and Differentiation. 2016. 23:1219-31